Big Pharma Manufacturers

The U.S. accounts for about 40 percent of the worldwide sales of both pharmaceuticals and medical devices and is home to some of the biggest manufacturers in each industry. By revenue, in 2019, the worldwide pharmaceutical industry saw revenue of about $1.3 trillion and the medical device market was about $500 billion worldwide. While great strides have been made in treatment of diseases and disorders, each year hundreds of thousands of people are injured by drugs and devices.

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Pharmaceutical Manufacturers

Medical Researcher Explores New MedicineMillions of crucial medical treatments would not be available without the companies that devote time and resources to developing and manufacturing them. While manufacturing companies save millions of lives each year, they may also jeopardize them. A number of well-known manufacturing companies currently face thousands of lawsuits for defective drugs and devices. Additionally, many of these companies withhold life-threatening information in favor of more sales and profits.

Boehringer Ingelheim

Boehringer Ingelheim is a German pharmaceutical manufacturer that has operations in 140 countries. The company has products for both animals and humans and focuses on cardiac and metabolic disease, respiratory medicine, oncology, immunology, central nervous system and retinal disorders. Boehringer Ingelheim may be facing thousands of lawsuits for medical injuries caused by some of their medications including anticoagulant Pradaxa and Type 2 diabetes medication, Tradjenta.


Pfizer is a pharmaceutical giant headquartered in New York City with operations in 180 countries around the world. Pfizer produces products in a wide range of therapeutic areas including internal medicine, oncology, rare diseases, immunology, and vaccines with a focus in developing science of biosimilars and gene therapies. The company currently faces a growing number of lawsuits from patients who were harmed by taking Pfizer drugs such as Effexor, Zolft, Celebrex, Chantix, and Bextra.

Eli Lilly

Eli Lilly and Company is an American pharmaceutical manufacturer based in Indiana and is one of the oldest drug companies in the world. Founded by a pharmacist, Eli Lilly introduced many innovations that made medicine easier to take such as gelatin capsules, sugar coatings and flavorings. It was the first producer of insulin and a major force in the U.S. pharmaceutical market, particularly in antibiotics and psychiatric medicines but has come under fire over the past several years due to injuries caused by some of its medications.


AbbVie is a pharmaceutical manufacturer which is a spinoff of Abbott Laboratories, specializing in biopharmaceuticals including the blockbuster drug, Humira. AbbVie has operations in 175 countries and focuses on complex disorders like immunology, virology, oncology and neuroscience. AbbVie is the manufacturer of the blockbuster medication, Humira is the largest selling drug in U.S. history and is used to treat autoimmune disorders such as Rheumatoid Arthritis, Psoriasis, and Crohns disease.

Daiichi Sankyo

Daiichi Sankyo is a Japanese pharmaceutical company which sells products in over 50 countries around the world. It is headquartered in Tokyo and got its start as two, separate companies and have been pioneers in cardiovascular, gastrointestinal and immunology with the discovery and production of Adrenalin, a pharmaceutical form of the naturally occurring neurotransmitter, epinephrine along with a number of legacy medications to treat infectious diseases and other illnesses.


GlaxoSmithKline (GSK) is a pharmaceutical giant with operations in over 100 countries and a history which began in the 1840s. Its business is divided into three divisions: pharmaceuticals, vaccines, and consumer healthcare. GSK is the fourth largest pharmaceutical manufacturer and its consumer health division currently markets notable brands including AquaFresh toothpaste, Nicorette gum, and Excedrin pain relief. GSK pharmaceutical products have notably included antidepressants Paxil and Wellbutrin, ED medication Levitra, and diabetes medication Avandia which has resulted in a number of lawsuits.


AstraZeneca is a multinational pharmaceutical company based in the UK. AstraZeneca is currently focused on cardiovascular, metabolic, and renal disease, respiratory and immune function, and cancer treatment. The company manufactures big-sellers like diabetes medications Farxiga, Byetta and Bydureon and Ulcer medications Prilosec and Nexium which have been accused of causing serious drug injuries.


Endo is a global pharmaceutical company based in Dublin, Ireland with U.S. headquarters in Pennsylvania. In the U.S., Endo Pharmaceuticals focuses on Urology, Endocrinology, Orthopedics and Aesthetics and manufactures well-known medications such as Percocet and Lidoderm as well as a number of testosterone replacement products including Testim, Testopel, Striant and Fortesta.

Takeda Pharmaceuticals

Takeda Pharmaceuticals was founded in 1781 in Osaka, Japan. It is currently the largest pharmaceutical company in Japan and one of the largest in the United States. Takeda’s type 2 diabetes drug Actos grew to become one of the best-selling diabetes treatments. However, numerous studies have shown that Actos can significantly increase the risk of congestive heart failure and bladder cancer. A number of Actos patients filed lawsuits against Takeda for injuries caused while taking Actos.

Bristol-Myers Squibb

Bristol-Myers Squibb (BMS) is one of the world’s largest pharmaceutical manufacturers with focus on oncology, virology, and immunology along with cardiovascular, metabolic, and neurological disorders. Some of its most notable products have resulted in numerous lawsuits including diabetes medications Farxiga, Glucophage, Byetta and Bydureon, anticoagulants Plavix and Eliquis, and antipsychotic Abilify along with others.

Merck & Co.

Founded in 1668, Merck & Co. has grown to become a global manufacturing giant and one of the most well-known companies in the world. It is known for products such as Coppertone sunscreen and over-the-counter allergy drug Claritin. Merck currently faces a number of lawsuits for products such as osteoporosis drug Fosamax, birth control device NuvaRing, diabetes medication Januvia, and Propecia, used for prostate disorder.

Procter & Gamble

Procter & Gamble is one of the world’s largest manufacturing companies with operations in over 80 countries. P&G specializes in household products, consumer goods and personal care items with notable brands including Crest, Tide, Pampers, CoverGirl and Secret. The company has also manufactured a number of pharmaceutical products including Prilosec OTC and osteoporosis drug, Actonel.

Johnson & Johnson

Johnson & Johnson is perhaps the most well-known health product manufacturer in the world. The company has faced a series of product recalls for poor quality and unusual odors caused by contaminants. Tylenol is one of Johnson & Johnson’s most popular products. While Tylenol can be found in nearly every household in America, it can have devastating side effects. A number of patients have experienced liver damage from Tylenol and the company has faced serious challenges after its talcum-based Johnson’s Baby Powder was linked to ovarian cancer.

Medical Device Companies

C.R. Bard

C.R. Bard is a medical device manufacturer based in New Jersey which was acquired by another medical products company, Becton Dickinson (BD) in 2017. Under the BD name, Bard manufactures medical products and equipment for a variety of medical, hospital and surgical settings. Bard was the original manufacturer of the Foley catheter, and still provides a number of urology, vascular and oncology products but has come under fire for some of its vaginal mesh devices and IVC filters.


DePuy Orthopaedics is a subsidiary of Johnson & Johnson. DePuy’s ASR Hip Resurfacing System and ASR XL Acetabular System were recalled due to severe side effects. The metal-on-metal components within the implants rubbed together and released metallic debris inside the bodies of a number of patients. This led to debilitating conditions such as metallosis, or metal poisoning.


Stryker Orthopaedics is the largest orthopedics device manufacturer in the world. Stryker manufactures products for joint replacement, spinal surgery, craniomaxillofacial medicine, sports medicine, and trauma and also offers products medical-surgical, neurotechnology and other areas. The company is well-known for its advancements in implants for the shoulders, hips, and knees, some of which have resulted in serious injury and thousands of lawsuits including hip replacement devices ABG II and Rejuvenate.

Zimmer Biomet

Zimmer Biomet is a global medical device company based in Indiana, founded in 1927 as Zimmer Holdings, which became Zimmer Biomet Holdings in 2015 with the acquisition of competitor, Biomet. The company sells orthopedics devices and solutions in over 100 countries and remains focused on alleviating pain through development of products used for musculoskeletal health conditions. Both Zimmer and Biomet have faced thousands of lawsuits for injuries caused by their popular knee and hip replacement devices.


Coloplast is a Denmark-based supplier of medical care products including ostomy care, continence care, wound and skin care, and products for interventional urology including implantable mesh and slings. Coloplast’s U.S. headquarters are in Minneapolis, Minnesota. Coloplast has faced thousands of lawsuits for harm caused by its transvaginal mesh and bladder sling medical devices.

Cook Medical

Cook Medical is the largest private, global medical device manufacturer, whose product lines include devices for cardiology, gastroenterology, gynecology, and other areas. One of the largest divisions of Cook Medical manufactures transvaginal mesh products which have resulted in serious injury for many women who received them for uterine and bladder repair.

Boston Scientific

Boston Scientific is a medical device company which manufactures diagnostic and interventional treatment devices in a variety of therapeutic areas. The company is focused on less-invasive technologies for endoscopy, interventional cardiology and rhythm management, neuromodulation, peripheral therapies, urology, and pelvic health. Boston Scientific has faced a number of device injury lawsuits for their medical devices including thousands of transvaginal mesh lawsuits.